My 4 year old Yorkie was put on apoquel. Died in hospital where we had to carry her. Hydroxyzine dosage for dogs. Bloods came back as normal and vet said it wasnt the Apoquel that caused the fits. His spleen burst And blood was leaking into his abdomen they took blood and x-rays and found out that he had also cancer in his lungs, from the medication I would never put any dog on this medication ever and called the company and they still still will not say that the medication causes that issue even though he was healthy happy and the best dog and we had to put him to sleep at 4 1/2 years old due to him taking Apoquel. People need to look at tbeir vetwhat has been tried first. The first day I thought he had something stuck in his throat but since then it hasnt stopped so here I am I decided to look up the side effects and found this site. A blinded, randomized, placebo-controlled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (Apoquel) in client-owned dogs with atopic dermatitis. I am a Healthcare professional and I somehow missed important information. You may want to remember the golden rule..if you dont have anything nice to say, then dont say anything at all. Unbelievable!!! Its been 2yrs of no Atopica. I know my Dog, . I now wonder if he had environmental allergies. I know that an itching dog suffers, but I will try whatever I can to give her to be comfortable, and I know between the prednisone and apoquel she is probably being killed from the inside and I cannot do that to her. Enter other medications to view a detailed report. While the exact mechanism of action is not known, it is thought that Apoquel works by inhibiting the activity of Janus kinase enzymes, which are important in signal transduction in many cells, including those involved in the allergic response. This drug should be removed from the market. If this discomfort is due to an allergy, a skin infection, or dermatitis, your vet may prescribe an antihistamine to relieve the symptoms and make your pooch more comfortable. These medications may cause some risk when taken together. Where do you find these complaints on the site? Ive never had major issues with veterinarian medicines for my pets. My dog has very bad allergies. Her white hair on her lower back turned red from her itching and got worse with bumps all over her lower back. Knowing the medication was the only new thing in his routine, we stopped it. Poor little guy. Both hydroxyzine HCl (hydrochloride) and hydroxyzine pamoate have the same active ingredient, hydroxyzine. Save my name, email, and website in this browser for the next time I comment. our 17 year old cairn terrier has been on Apoquel for 4 mos. After reading almost all of the comments on here I would think you would all exchange info and file a Class Action Lawsuit against the makers of this drug, the FDA for negligence, at least. I encourage each and every person considering apoquel to make sure you are educated. I was too afraid so I gave her 1/2 dose and I thought she had a mild shake. For us, Apoquel is a bad drug. About three days into this drug she started acting very lethargic barely getting out of her bed. I watch the Zeljanz commercial which is basically a very similar drug for humans.listening to all the huge long list of potential side effects.cancers have happened and they say it like potential for thunderstormslike no big deal. She cant see or smell food an inch from her nose! Dogs on Cytopoint typically need injections every four to eight weeks. Finally after several hours he ate his food and drank enough water. Customer: Hi, he has had seasonal allergies for a years. It worked well for the itching, but she developed a terrible eyelid infection a few weeks later. I can not believe this is on the market with how many dogs have had issues from it. One studyfound that 54% of dogs with atopic dermatitis that had been given antihistamines to treat the condition responded favorably. I at least know for sure 1 drug I would Never Try and that is this Apoquel. When I do find him upstairs he is comatose and has vomited all around the house and done a poo in the family room. which is causing more messes to clean up. Last night she trembled constantly and I was extremely worried about her. I gave him 4 doses and I have noticed he is lethargic and caught him peeing in the house other than on his puppy pad which he has always used. This was very traumatic to witness in a 200 lb.dog. Norman weighs roughly 20 pounds, so he takes a 5.4mg pill. His allergies are now extreme and he has no fur on the back of his paws/legs. Sooooo happy with it but All of a sudden, she has developed a whole new set of even more significant and really scary issues: She started going kiki accidentally, when she would start digging on furniture, in bed, where ever! She use to sleep like a baby but the last few nights has kept me awake. I love my dog way too much to simply take the risk. Then Vet encouraged us to continue every 2nd day which we did. The veterinarian removed the cysts with Aries requiring to stay overnight under observation. Im on this site after its too late. Wow!!! Can Apoquel be used with other medications? A huge shout to today's VetGirl guest blogger is by Dr. Nicole Heinrich, DACVD of McKeever Dermatology Clinics. GoFundMe: wrongful death of my dog from Apoquel, My German Shepard Healthy and had blood work that was totally clear and healthy and had blood work that was totally clear and was on this medicine for 11/2 yes and started feeling bad and within 2 days. This saved his life. If you've a medium or small-sized pup the . When we took him in, the nurse noticed bumps on his back and the vet (a new one) decides that it is a skin infection and prescribes(without permission) Cefpodoxime and Apoquel. In April he received Lyme vaccine and shortly thereafter developed skin infection requiring steroids. He was a healthy and playful boy and certainly did not act his age!!! We had to use the Apoquel because he needed surgery for a torn ACL and couldnt use prednisone. dog? 500 grams liver, 2 handfuls of shredded cheese and I serve it up with a dollop of natural yoghurt and 2 tablespoons of Omega blend oil (vets all natural). University) This is what I believe happened to my Baby Girl Still itching and the straw that broke the camels back was seizures. All in all, very mild side effects as opposed to other anti-pruritic medication. FDA approval of APOQUEL is based on results of two clinical trials conducted in the Then my other boy has high liver enzyme. Of those 247 dogs, they removed 26 dogs from the study for one reason or another and 18 were euthanized. Then came the motor coordination hiccups. We lost our Ginny girl. THIS DRUG KILLED MY DOG. My old boy Hamish is worse. I saw another yorkies mom on here post the almost identical thing as my girl is. Will be calling the vet on Monday, fingers crossed she goes back to herself today! He kept saying its a new drug. Thats right, turns them right off, which is great if all you care about is preventing the itchiness but not so great if you want a healthy dog. He chews at his hind quarter, scratches at his paws and ears keeping me up at night. My vet prescribed Apoquel for her and she immediately threw up and became very listless. We tried Benadryl, Temaril-P & homeopathic remedies. He had to have the dosage raised today after 2 seizures this morning. Apoquel cannot be used for dogs under one year or breeding, pregnant, or lactating . Histamines are compounds in the body which are responsible for the symptoms we experience when we are allergic to something. My senior Dog, was put on apoquel 2 weeks ago. Dogs treated with Apoquel works within four hours, controls allergy itching within 24 hours, and is safe for short-term and long-term usage. The Vet eventually suggested Apoquel. My 12 1/2 yr old westie has been very healthy for his whole life until last august . I fear for anyone giving this to their dog. My 10 year old Rat Terrier was prescribed Apoquel 3.6 for 30 days on Oct 6, 2017 due to her itching. We always recommend that you follow your vets advice when it comes to canine medication. A small study of 299 dogs- 50% of the dogs took the placebo medication, and most dropped out of the study. Just to note a couple of ignorant owners from the above blog. He never does that, he always tells me when he has to go out. Please help if anyone knows Im going to stop giving to her for the rest of the week and see what happens. They say it can take a month per year of your pets life to work. For the prescriptions !!! She told me not to take the 2 bp meds and antistroke meds the traditional vet prescribes that diagnoses the kidney problem. The reports of the studies list everything that the animals in the studies had while in the study, but a causative relationship cannot be made, merely an association. The neurologist said by default he had to dx her with epilepsy. My yellow lab took apoquel with great successso we thought. We used another medicine that was for his condition and it helped but then it stopped working. Some of the horror stories above are frightening. My dog is so sick after two weeks of Apoquel Customer: She's an American bulldog with horrible allergies. We went to the vet because she was quite lethargic. When we arrived, Ginny pooped alot which I thought was because of the travel. DO NOT GIVE THIS MEDICINE TO YOUR ANIMAL. Steroids side effects include CHF, pancreatitis, immunosuppression among many others. Normal levels are between 0-200 my dogs were 2,000. Hydroxyzine belongs to a family of drugs called antihistamines. Within the first 12 hours he developed runny poop and lethargy. Drugs.com is where I found all the horrible side effects of the drug and it was too late. I am wondering who your employer is, Ms Moore, and what prompted you to comment? And now hes scratching like crazy again. There are 384 drugs known to interact with zonisamide, along with 11 disease interactions, and 1 alcohol/food interaction. Im wondering If the medicine comes out of his system will he return to his normal form or is the insulin the only option at this point? None of these worked brilliantly but they did have an effect on reducing some of his symptoms. Redness . He also had diarrhea and itching. Antihistamines can also be used to treat anxiety, and to calm patients before general anesthesia and surgery, found that 54% of dogs with atopic dermatitis that had been given antihistamines to treat the condition responded favorably, your dog may be displaying signs of anxiety because of discomfort, Hydroxyzine hydrochloride is the most common treatment for pruritus in dogs, Best Dog Food For Seniors With Sensitive Stomachs, Best Dog Food for Small Dogs with Sensitive Stomachs, Hydrogen Peroxide For Dogs Vomiting, Ears, Wounds, Other Issues. Dogs have 10 times more mast cells on their skin than people do. Thank you for any help. You are using fear tactics to prevent people from using certain medications, while then offering your own pet medications/shampoos/etc. but I had no idea so many were having issues long term. It's . He sometimes paws at his bed at night and urinates like some of the pet owners stated above. Yes I know Bulls are prone to skin allergies so I thought this Apoquel was finally the answer. She had a brain tumor. We just make sure to take him out frequently to be safe. It works well for mild allergic reactions, such as an insect bite or sting. It can also be used for more long-term allergies but has varying results. to the manufacturer of Apoquel, this drug can predispose stand up hes so weak. So, does Apoquel stop itching? After an examination, they may deem it appropriate to prescribe an antihistamine as part of the treatment plan. The rate of adverse events overall was low (<5%) and included She ended up on 2 antibiotics and eye drop for 3-4 weeks. I am not a qualified vet or anything, just something I think might be her problem. My dog died this past Sunday and had all of the Symtoms I have seen in most of this comments, he was clumsy and peed in weird places out of nowhere I knew what my dog ate and how heathy he was until this drug was giving to him. I think they lied. 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